The Malaysia Airlines jet disappeared on March 8 last year when it inexplicably veered off course en route from Kuala Lumpur to Beijing with 239 people on board, and a colossal multinational hunt for the aircraft proved fruitless.
But last week's discovery of a 2m-long wing part called a flaperon on the French Indian Ocean island of La Reunion raised fresh hopes for relatives desperate for answers.
The Boeing 777 piece has been taken to the southwestern French city of Toulouse, where it will undergo the high-profile examination.
A French source close to the case says the case containing the wing part will be opened early afternoon today in the presence of French and Malaysian experts, Boeing employees and representatives from China, the country that lost the most passengers.
The source who wished to remain anonymous adds that it is as yet unclear whether their conclusions will be announced on the same day or later
Australia's deputy Prime Minister Warren Truss has said, meanwhile, that official word on whether the flaperon is from MH370 could come this week.
Truss added that Australia's national science agency had confirmed that drift modelling showed debris could have been carried by wind and currents to La Reunion, some 4,000 kilometres (2,500 miles) from the region where MH370 was thought to have gone down.
Jean-Paul Troadec, the former head of France's BEA agency that investigates air accidents, says the analysis will focus on two issues, whether the flaperon belongs to MH370 and if so, whether it can shed light on the final moments of the plane.
He pointed for instance to the paint on the piece, which has already been confirmed as coming from a Boeing 777 plane as a key element of the probe.
"Every airline paints their planes in a certain way and if the paint used is used by Malaysia Airlines and other companies, there may be more certainty," he said.
Pierre Bascary, former director of tests at the French Defence Procurement Agency, where the analysis will take place, adds that the airline may have written maintenance information on the piece such as "Do Not Walk".
"The phrase used and the way it was written also gives an idea of the origin of the plane," he said.
Troadec says experts will also examine the way the part detached itself from the wing.
"Was it in a violent impact with the sea or not?. This piece looks like it is in good condition, it doesn't look like the part of a plane that fell vertically in the water at 900 kilometres (600 miles) an hour," he said.
He adds that experts may also look for traces of an explosion or fire.
Scientists have pointed to the barnacles that are attached to the flaperon, saying these could give an idea of how long the piece has been in the water, and perhaps where it has been.
"If it has cold-water barnacles on it that might tell them it went down further south than they think. Or if it's got only tropical barnacles, that might tell them it went down further north," said Shane Ahyong, a crustacean specialist from the Australian Museum.
But he says some oceanic barnacles are so widespread that pinpointing their precise origin would likely be impossible given the lack of genetic and population information about them.
Troadec warns that the analysis is highly unlikely to give any clues as to why the plane mysteriously diverted off course.
"One should not expect miracles," he said.
For the victims' loved ones, though, any tangible piece of information is likely to help them in seeking closure, according to psychologist Carole Damiani, who specialises in helping the families of people who died in disasters.
"The grieving process is about untying oneself from someone, accepting that they will not be found and they have gone forever.
"When someone goes missing, it is difficult to say 'I will stop looking. You need people to say 'he is dead, you are allowed to start the grieving process and undo this bond'," she said
Damiani says that knowing where the plane crashed would also bring some closure.
"When there is a 'natural' death, everyone always asks 'what were their last words, what were the last moments like.' And in this case, there is none of that. Families need to know how and why."
South Africa is representing as always!Stacey & J Sbu 5 hours ago
He aimed for a culinary masterpiece but ended up with a foodie fail...Stacey & J Sbu 6 hours ago